Figure 5. Early ERN1 and ALPK1 knockdown tumors differ in expression pattern or phenotype from control tumors.

A. Volumes of tumors (in mm³) derived from control, siERN1 or siALPK1 transfected MDA-MB-468 cells 16 days after transplantation. Depicted are the mean values ± SEM. B. Volumes of tumors (in mm³) derived from control, shERN1 or shALPK1 transfected MDA-MB-468 cells 16 days after transplantation. Depicted are the mean values ± SEM. C. The panel depicts representative images of tumors sections derived from control, shERN1 and shALPK1 transfected MDA-MB-468 cells (from top to bottom) 16 days after transplantation. Histochemical staining is indicated on the top from left to right: H&E (hematoxylin and eosin), K5 (keratin 5), K8 (keratin 8), GATA3 and Ki67. Scale bars represent 100 μm.