Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
| Construct | Yield [mg/L cell culture] | Biol. Activity (SEM) EC50 [pM] | Affinity CD16 [nM] | Avidity CD19 [nM] |
|---|---|---|---|---|
| SPM-1 | 1.7 - 5.5 | 11 ± 3 | 12.0 ±1.5 | 17.5 ± 0.4 |
The affinity is the equilibrium binding constant KD for monovalent binding to CD16 on stably transfected CHO-CD16 cells; the avidity is the KD value of the molecule for bivalent binding to CD19-bearing SEM target cells.
