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. 2016 Nov 4;7(50):83392–83408. doi: 10.18632/oncotarget.13110

Table 2. Surface expression of CD19 and EC50 values for RDL by SPM-1 with different malignant B lymphoid cell lines as targets.

Cell Line Subtype of malignancy CD19 density [#] EC50 (range) [pM]
SEM Pro-B (mixed lineage) 42,600 ± 10,700 5.6 (2.5 – 10)
NALM-6 Pre-B 26,700 ± 11,400 6.1 (1.8 – 17.3)
RAJI Burkitt's Lymphoma 31,900 ± 22,800 16.5 (5.4 – 38.5)
ARH-77 Mature B (myeloma) 2,400 ± 1,200 79.4 (38 – 645.3)

Antigen densities are given in copy numbers per cell.