Table 2. Comparison between low and high MTV/TLG groups.
| Clinical Factors | No. of patients (%) | P value b | No. of patients (%) | ||||
|---|---|---|---|---|---|---|---|
| Total | Low MTV a | High MTV a | Low TLG a | High TLG a | P value b | ||
| Age | 0.607 | 0.737 | |||||
| ≤60 y | 53 | 28(61) | 25(56) | 26(57) | 27(60) | ||
| >60 y | 28 | 18(39) | 20(44) | 20(43) | 18(40) | ||
| NCCN-IPI score | <0.001 | <0.001 | |||||
| 0-3 | 52 | 37(80) | 15(33) | 35(76) | 17(38) | ||
| 4-8 | 39 | 9(20) | 30(67) | 11(24) | 28(62) | ||
| Ann Arbor Stage | 0.003 | 0.037 | |||||
| I/II | 34 | 24(52) | 10(22) | 22(48) | 12(27) | ||
| III/IV | 57 | 22(48) | 35(48) | 24(52) | 33(73) | ||
| B symptoms | <0.001 | 0.008 | |||||
| No | 41 | 29(63) | 12(27) | 27(59) | 14(31) | ||
| Yes | 50 | 17(37) | 33(73) | 19(41) | 31(69) | ||
| Performance status | 0.002 | 0.037 | |||||
| ECOG 0-1 | 71 | 42(91) | 29(64) | 40(87) | 31(69) | ||
| ECOG >1 | 20 | 4(9) | 16(36) | 6(13) | 14(31) | ||
| No. of extranodal sites | 0.072 | 0.17 | |||||
| 0-1 | 55 | 32(70) | 23(51) | 31(67) | 24(53) | ||
| 2 or more | 36 | 14(30) | 22(49) | 15(33) | 21(47) | ||
| LDH level | 0.002 | 0.002 | |||||
| normal | 55 | 35(85) | 20(44) | 35(76) | 20(44) | ||
| elevated | 36 | 11(24) | 25(56) | 11(24) | 25(56) | ||
Abbreviations: MTV, metabolic tumor volume; TLG, total lesion glycolysis; NCCN-IPI, National Comprehensive Cancer Network-International Prognostic Index; ECOG, Eastern Cooperative Oncology Group; LDH, lactate dehydrogenase.
a
MTV and TLG were dichotomized by respective median values.
b
Pearson's chi-square test.