Table 4. Associations between GAS5 rs145204276 and Lymph node metastasis and Distant metastasis of CRC.
| Genotypes | Event (n, %) | No event (n, %) | OR (95% CI)a | Ptrend |
|---|---|---|---|---|
| Lymph node metastasis | ||||
| ins/ins | 286 (56.1%) | 452 (50.8%) | 1.00 (Reference) | |
| ins/del | 194 (38.0%) | 356 (40.0%) | 0.86 (0.68-1.08) | |
| del/del | 30 (5.9%) | 82 (9.2%) | 0.58 (0.37-0.90) | |
| del vs ins | 0.80 (0.68-0.95) | 0.010 | ||
| Distant metastasis | ||||
| ins/ins | 117 (57.1%) | 621 (52.0%) | 1.00 (Reference) | |
| ins/del | 78 (38.0%) | 472 (39.5%) | 0.88 (0.64-1.20) | |
| del/del | 10 (4.9%) | 102 (8.5%) | 0.52 (0.27-1.02) | |
| del vs ins | 0.80 (0.63-1.02) | 0.070 |
a
adjusted by age, gender, alcohol and smoking status