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The RuII(bpy)3 surface mimetics and their PPI counterparts cyt c and CCP. A) RuII(bpy)3 complexes 1 and 2, B) the cyt c/CCP interaction, with cyt c in pink and CCP in blue (PDB ID: 1U75),34 and C) the interaction faces of cyt c (left) and CCP (right), showing a ring (red circle) of basic amino acid residues (blue) on cyt c and a complementary patch (blue circle) with acidic amino acid residues (red) on CCP.
