Table 2.

Changes in serum phosphorus concentrations, corrected calcium levels, intact‐PTH levels, protein catabolic rate, and Kt/V (per protocol set)

	PA21 group n = 100	Sevelamer group n = 92
Serum phosphorus concentration (mmol/L), mean ± SD
Week −3	1.80 ± 0.27	1.76 ± 0.36
Week 0	2.51 ± 0.45	2.45 ± 0.39
End of treatment	1.62 ± 0.33	1.72 ± 0.33
Change from Week 0	−0.90 ± 0.53	−0.73 ± 0.45
Corrected serum calcium level (mmol/L), mean ± SD
Week −3	2.34 ± 0.13	2.32 ± 0.14
Week 0	2.24 ± 0.15	2.22 ± 0.14
End of treatment	2.29 ± 0.17	2.23 ± 0.18
Change from Week 0	0.05 ± 0.13	0.01 ± 0.15
Serum intact‐PTH level (ng/L), median (quartiles: 25% and 75%)
Week −3	162 (95, 263)	192 (116, 271)
Week 0	235 (176, 339)	282 (174, 386)
End of treatment	190 (123, 259)	228 (123, 348)
Change from Week 0	−52 (−118, −8)	−49 (−87, −5)
Protein catabolic rate (g/kg per day), mean ± SD
Week 0	0.889 ± 0.126	0.917 ± 0.151
End of treatment	0.872 ± 0.160	0.888 ± 0.152
Kt/V, mean ± SD
Week 0	1.541 ± 0.297	1.557 ± 0.293
End of treatment	1.507 ± 0.299	1.533 ± 0.271

Kt/V, urea clearance; PTH, parathyroid hormone.