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The severity of the phenotype in mice defective for multiple TFKs
| Cell type | More severe double KO phenotype when compared to single KO mice |
|---|---|
| B lymphocytes | BTK/TEC 42 |
| T lymphocytes | ITK/TXK 59, 61 |
| Platelets | BTK/TEC 65 |
| Osteoclasts | BTK/TEC 64 |
| Macrophages | BTK/TEC 62, 63 |
| Mast cells | BTK/TEC, BTK/ITK 66, 67 |
| Dendritic cells | Not reported |
| Erythroblasts/Erythrocytes | Not reported |
| Neutrophils | Not reported |
