Table 3.
Clinical outcome in children with cystic fibrosis able to perform lung functions, by level of care
| Cystic Fibrosis Centre | Shared | Local | P‐value | |
|---|---|---|---|---|
| Number | 163 | 31 | 19 | |
| Males (%) | 81 (49.7%) | 19 (61.3%) | 12 (63.2%) | P = 0.66 |
| Age [median years)] | 12.8 (9.5, 16.2) | 12.6 (9.5, 14.9) | 11.8 (8.7, 13.7) | P = 0.21 |
| Pancreatic insufficiency (%) | 134 (82.2%) | 28 (90.3%) | 17 (89.5%) | P = 0.21 |
| Anthropometry | ||||
| Height (cm) | 148.3 (129.0, 163.3) | 150.0 (130.0, 157.2) | 148.0 (129.2, 154.7) | P = 0.69 |
| Height z‐score | −0.14 (−0.84, 0.43) | −0.59 (−0.89, 0.12) | −0.24 (−0.76, 0.38) | P = 0.32 |
| BMI†(kg m−2) | 17.9 (15.9, 20.2) | 17.1 (15.9, 19.0) | 18.1 (17.6, 19.9) | P = 0.42 |
| BMI z‐scores | −0.12 (−0.74, 0.49) | −0.28 (−1.14, 0.42) | 0.12 (−0.24, 0.9) | P = 0.22 |
| P. aeruginosa (%) | ||||
| None | 68 (64.8%) | 15 (68.2%) | 5 (55.6%) | — |
| Present | 9 (8.6%) | 2 (9.1%) | 1 (11.1%) | — |
| Chronic | 28 (26.7%) | 5 (22.7%) | 3 (33.3%) | P = 0.41 |
| Lung function tests | ||||
| FEV1 (l) | 1.95 (1.4, 2.8) | 2.10(1.60, 2.70) | 1.80 (1.60, 2.40) | P = 0.85 |
| FEV1% predicted | 88.8%(75.8, 99.7) | 97.8 (80.6, 105.9) | 90.8% (77.6, 101.0) | P = 0.22 |
| Mean FEV1% | 83.2 (70.4, 94.3) | 87.3 (73.2, 101.1) | 83.8(66.5, 97.9) | P = 0.36 |
| FVC (litres) | 2.34 (1.73, 3.41) | 2.01(1.79, 3.55) | 2.33 (1.82, 2.99) | P = 0.93 |
| FEF25–75% | 1.7 (1.2, 2.7) | 2.0 (1.3, 2.8) | 1.9 (1.2, 2.6) | P = 0.71 |
Medians(M) and interquartile ranges (IQR) reported in brackets, unless otherwise stated. The P‐value is for any statistically significant difference in clinical outcome measures between the two of the groups of SES and Remoteness categories. BMI, body mass index; P aeruginosa, Pseudomonas aeruginosa; FEV1, forced expiratory volume in 1 s; FVC, forced vital capacity; FEF25–75, forced expiratory flow rate 25% to 75% of FVC.