Table 3.
Post hoc analysis of CNR1 × RLE interaction on headache with nausea in the separate study populations, and in the total population after controlling for study sites, neuroticism, lifetime depression and current depression and anxiety scores
SNP | A1 | Budapest | Manchester | Total population corrected for study site and depression related variables | ||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
OR | L95 | U95 | P | OR | L95 | U95 | P | OR | L95 | U95 | P | |||
1 | rs2180619 | G | 1.055 | 0.879 | 1.266 | 0.564 | 0.870 | 0.768 | 0.985 | 0.028 | 0.931 | 0.836 | 1.036 | 0.189 |
2 | rs806379 | T | 0.905 | 0.759 | 1.080 | 0.268 | 1.083 | 0.959 | 1.224 | 0.199 | 1.033 | 0.930 | 1.146 | 0.547 |
3 | rs1535255 | G | 0.977 | 0.791 | 1.208 | 0.830 | 0.923 | 0.788 | 1.081 | 0.322 | 0.935 | 0.820 | 1.067 | 0.319 |
4 | rs2023239 | C | 0.937 | 0.757 | 1.160 | 0.550 | 0.939 | 0.798 | 1.105 | 0.449 | 0.925 | 0.809 | 1.057 | 0.253 |
5 | rs806369 | T | 1.173 | 0.962 | 1.430 | 0.115 | 1.087 | 0.942 | 1.254 | 0.252 | 1.128 | 0.998 | 1.275 | 0.054 |
6 | rs1049353 | A | 0.875 | 0.711 | 1.077 | 0.209 | 0.834 | 0.726 | 0.959 | 0.011 | 0.840 | 0.744 | 0.948 | 0.005 |
7 | rs4707436 | A | 0.869 | 0.706 | 1.068 | 0.181 | 0.856 | 0.745 | 0.983 | 0.028 | 0.854 | 0.757 | 0.964 | 0.010 |
8 | rs12720071 | G | 1.176 | 0.853 | 1.621 | 0.324 | 0.910 | 0.721 | 1.150 | 0.431 | 0.964 | 0.797 | 1.164 | 0.700 |
9 | rs806368 | C | 0.953 | 0.783 | 1.160 | 0.630 | 0.943 | 0.811 | 1.095 | 0.440 | 0.941 | 0.831 | 1.065 | 0.335 |
10 | rs806366 | T | 0.818 | 0.677 | 0.988 | 0.037 | 0.829 | 0.720 | 0.955 | 0.009 | 0.814 | 0.722 | 0.917 | 0.0007 |
11 | rs7766029 | T | 1.026 | 0.848 | 1.240 | 0.792 | 1.149 | 1.013 | 1.303 | 0.030 | 1.104 | 0.990 | 1.232 | 0.076 |
Bold, nominally significant effects; italic, trend effects; L95‐U95, 95% confidence interval; OR, odds ratio; P, significance.