Fig. 2.
The gliovascular unit. Astrocytic endfeet are tightly anchored to the vascular surface by interactions between the dystrophrin-dystroglycan complex (DDC) and proteins that make up the basement membrane (refer to insert). Tight and adherens junctions link endothelial cells together to form the blood-brain barrier (BBB), while integrins connect the endothelial cells to the basement membrane