GPS promoted renal excretion of uric acid and improved renal function in hyperuricemic rats (n=8). NC – normal control; LE – Lipid Emulsion contained high cholesterol and high fat food group; APC – Lipid Emulsion with positive control of Allopurinol group; BPC – Lipid Emulsion with positive control Benzobromarone group; GPS-H – Lipid Emulsion with high dose of Gypenosides (60 mg/kg body weight); GPS-L – Lipid Emulsion with low dose of Gypenosides (15 mg/kg body weight). The effect of GPS on Urine UA (A), Urine Cr (B), Serum Cr (C), Serum BUN (E), kidney index (D) and FEUA (F) were detected at 8 weeks after administration. The data were expressed as mean ±SD. #
P<0.05; ##
P<0.01, compared with normal control group; * P<0.05; ** P<0.01, compared with Lipid Emulsion group.