GPS modulated the expression of mURAT1, mGLUT9 and mOAT1 in the kidney. NC – normal control; LE – Lipid Emulsion contained high cholesterol and high fat food group; APC – Lipid Emulsion with positive control of Allopurinol group; BPC – Lipid Emulsion with positive control Benzobromarone group; GPS-H – Lipid Emulsion with high dose of Gypenosides (60 mg/kg body weight); GPS-L – Lipid Emulsion with low dose of Gypenosides (15 mg/kg body weight). The effect of GPS on mURAT1 (A), mGLUT9 (B), mOAT (C) were detected at 8 weeks after administration. The data were expressed as mean ±SD. #
P<0.05; ##
P<0.01, compared with normal control group; * P<0.05; ** P<0.01, compared with Lipid Emulsion group.