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. 2017 Mar 13;12(3):e0173855. doi: 10.1371/journal.pone.0173855

Table 1. The characteristics of the study subjects with transient elastography measurement (n = 76) available by AF status.

AF (n = 36) non-AF (n = 40) p-value
Gender, n (%) (men) 29 (81%) 32 (80%) 0.952
Age (years) 73 (± 5) 72 (± 5) 0.285
BMI (kg/m2) 30.2 (± 4) 30.1 (± 4) 0.964
Waist (cm) 103 (± 11) 103 (± 13) 0.920
Systolic blood pressure (mmHg) 132 (± 24) 139 (± 18) 0.128
Diastolic blood pressure (mmHg) 72 (± 11) 74 (± 11) 0.346
Heart rate (/min) 69 (± 14) 70 (± 13) 0.581
Alcohol/week (g) 37 (± 54) 37 (± 48) 0.964
Smoking (pack years) 15 (± 24) 12 (± 20) 0.639
Hypertensives, n (%) 31 (86%) 32 (80%) 0.480
CAD, n (%) 15 (42%) 11 (28%) 0.194
LVMI (g/m2)** 122 (± 24) 126 (± 27) 0.534
LAD (mm)** 49 (± 9) 40 (± 5) <0.001
CKD-Epi (ml/min) 78 (± 19) 85 (± 11) 0.062
Leptin (ng/L) 16 (± 12) 17 (± 19) 0.777
Adiponectin (ug/mL) 14 (± 9) 12 (± 6) 0.226
Resistin (ng/mL)* 13 (± 5) 10 (± 3) 0.108
ALT (U/L) 28 (± 19) 30 (± 16) 0.691
GGT (U/L) 53 (± 31) 35 (± 29) 0.011
Alb (g/L) 39 (± 3) 41 (± 3) 0.030
Cholesterol (mmol/L) 4.2 (± 0.9) 4.5 (± 0.9) 0.137
LDL-cholesterol (mmol/L) 2.4 (± 0.7) 2.8 (± 1.0) 0.023
HDL-cholesterol (mmol/L) 1.3 (± 0.5) 1.3 (± 0.3) 0.992
HbA1C% (%) 6.4 (± 1.1) 6.2 (± 0.9) 0.344
hs-CRP (mg/L) 2.5 (± 2.4) 2.0 (± 2.3) 0.407
TSH (mU/L) 2.7 (± 1.7) 2.4 (± 1.2) 0.370
Quicki (L/mmol) 0.50 (± 0.10) 0.50 (± 0.07) 0.914
ACE inhibitor, n (%) 16 (44%) 13 (33%) 0.284
Lipid lowering drugs, n (%) 25 (69%) 20 (50%) 0.085

The continuous variables are expressed as mean values ± standard deviation and the categorical variables as absolute numbers, with percentage in brackets.

The differences were tested by the ANOVA test for the continuous variables and Pearson Chi-Squared test for categorical variables. The abbreviations are as follows: BMI, body mass index; CAD, coronary artery disease; LVMI, left ventricular mass index; LAD, left atrial diameter; CKD-Epi, Glomerular filtration rate by the Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation; ALT, Alanine aminotransferase; GGT, gamma-glutamyl transpeptidase; Alb, albumin; LDL, Low-density lipoprotein; HDL, High-density lipoprotein; HbA1C%, glycosylated hemoglobin A1C; hs-CRP high sensitive C-reactive protein; TSH thyroid stimulating hormone; Quicki (surrogate for insulin resistance, Quicki = 1/[log (fasting insulin)+log (fasting glucose)]); ACE, angiotensin converting enzyme inhibitor. The reported heart rate is the heart rate of the third measurement of the blood pressure. The reported systolic and diastolic blood pressures are the means of the second and third blood pressure measurements during the control visit. Of 36 subjects with AF (mean duration 109 months), 10 had paroxysmal (mean duration 117 months, range 35–226 months) and 26 chronic (mean duration 106 months, range 27–303 months) AF.

* Data available on 24 subjects

** Data available on 75 subjects.