Skip to main content
. 2017 Feb 27;13(2):e1005407. doi: 10.1371/journal.pcbi.1005407

Fig 2. Young's moduli of rat hippocampal neuronal subcompartments determined by AFM.

Fig 2

Histograms of Young’s moduli of rat hippocampal (A) soma, (B) dendrites, (C) axons, and (D) axons treated with 20μm Latrunculin B. The median Young's modulus of the soma is 0.7 ± 0.2 kPa (A), of dendrites is 2.5 ± 0.7 kPa (B). For the axon plasma membrane, the median Young’s modulus is 4.6 ± 1.5 kPa (C). When axons were treated with Latrunculin B (20μm, 1 hour) the median value of the axon plasma membrane Young’s modulus was reduced to 2.2 ± 0.6 kPa. Number of samples (N = 2), total number of tested neurons (n = 8). N = 1 and n = 6 for axon + Latrunculin B. (E) Box-whisker plots of mean Young's moduli of the soma, dendrites, axon, and axon treated with Latrunculin B. *** indicates statistical significance of p < 0.001 (Kruskal-Wallis test).