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. 2017 Feb 27;13(2):e1006623. doi: 10.1371/journal.pgen.1006623

Fig 4. Transgenic miR-17~92 expression shifts target mRNAs from heavy to light polysomes.

Fig 4

(A) A representative polysome profile of activated B cells, from two biological replicates for each genotype. Numbers inside the graph indicate the number of ribosomes associated with mRNA. (B) Distribution of miR-21 and miR-17~92 in the sucrose gradient in WT B cells. (C) Distribution of miR-17~92 target mRNAs in the sucrose gradient in WT and TG B cells. β-Actin mRNA (Actb) is enriched in heavy polysome fractions and is used as an internal control.