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ERK2 is a gene target of miR-543.
Notes: (A) The mRNA expression level of ERK2 in 4 breast cancer cell lines. (B) The relationship between ERK2 and miR-543 was assessed by Luciferase reporter assay. (C) The expression of MDA-MB-231 and MCF-7 in different groups n=5, *P<0.05, **P<0.01 vs MDA-MB-231 or mutant group.
Abbreviations: ERK, extracellular signal-regulated kinase; UTR, untranslated region.
