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. 2017 Mar 7;12:1827–1840. doi: 10.2147/IJN.S130539

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© 2017 Zhang et al. This work is published and licensed by Dove Medical Press Limited

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In vitro antitumor activity against prostate cancer cells. The cytotoxicity of Dox@PAH-cit/PDA, free Dox, and PAH-cit/PDA on PC3 (A), DU145 (B), LnCap (C), and cells. (D) The photothermal effect of prostate cancer cells treated by Dox@PAH-cit/PDA NPs with or without NIR irradiation at a power density of 2 w/cm² for 15 min. *P<0.05 was calculated by using Student’s t-test.

Abbreviations: Dox, doxorubicin; NIR, near-infrared reflection; NP, nanoparticle; PAH-cit, poly(allylamine)-citraconic anhydride; PDA, polydopamine.