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. 2017 Mar 7;12:1827–1840. doi: 10.2147/IJN.S130539

Figure 3.

Figure 3

(A) Cellular uptake of free Dox and Dox@PAH-cit/PDA NPs in PC3 cells revealed by CLSM images; scale bar =50 µm. (B) Quantitative analysis of intracellular concentration of Dox after cells incubated with free Dox or Dox@PAH-cit/PDA NPs. The ratio between Dox and cell protein concentration was detected. *P<0.05 was calculated by using Student’s t-test.

Abbreviations: CLSM, confocal laser scanning microscopy; DAPI, 2-(4-amidinophenyl)-6-indolecarbamidine dihydrochloride; Dox, doxorubicin; NP, nanoparticle; PAH-cit, poly(allylamine)-citraconic anhydride; PDA, polydopamine.