Figure 1.

(A) Setup used for Biochip Spray MS using a gold biosensor chip held in front of the MS inlet using an alligator clip and (B) spray obtained after adding 10 μL of methanol and applying a voltage of 5 kV. (C) Extracted ion chronogram for m/z 297.1333 ([DON + H]⁺) recorded in positive ion mode, as obtained from four different corners of a single 1 cm² square carboxymethylated dextran (CMD) modified gold chip. Five μL of a 1 μg/mL DON solution in methanol was pipetted on each corner, allowed to dry, and afterward sprayed using methanol. The time points when the high voltage (HV) was turned on and off are indicated by arrows.