Figure 2.
Resistance to major WHO antiretroviral drugs in HIV-1 from children in virological failure. The profiles of resistance to antiretroviral recommended by the WHO in 58 successful genotypes obtained in a representative sub-population randomly selected from 133 children with detectable plasma HIV-1 RNA viral load (nonresponders,V–) followed in the Complexe Pédiatrique Bangui. 3TC = lamivudine, ABC = abacavir, ATZ = atazanavir, AZT = zidovudine, d4T = stavudine, ddI = didanosine, DRV = darunavir, EFV = efavirenz, ETR = etravirine, FTC = emtricitabine, IDV = Indinavir, LPV = lopinavir, NFV = nelfinavir, NNRTI = non-nucleosidic reverse transcriptase inhibitor, NRTI = nucleosidic reverse transcriptase inhibitor, NVP = nevirapine, PI = protease inhibitor, r = ritonavir (which boosted other PIs), RPV = rilpivirine, SQV = saquinavir, TDF = tenofovir, TPV = tipravirine.