Table 4.

Percent of double pS422/p75 and single pS422, TOC1, TNT1, Tau C3 and p62 NFTs within the nbM by CTE pathological stage

	II	III	IV	p-value	pairwise comparison
pS422/p75	3.19 ± 3.30*	11.16 ± 7.4	24.68 ± 6.9	0.002a	II<IV
pS422	6.18 ± 5.2	26.65 ± 15.4	48.90 ± 23.6	0.001a	II<IV
TOC1	3.62 ± 2.9	14.13 ± 5.6	28.95 ± 24.3	0.001a	II<IV
TNT1	2.03 ± 2.8	10.01 ± 8.3	17.62 ± 10.5	0.008b	II<IV
Tau C3	1.80 ± 3.1	13.00 ± 5.9	15.64 ± 11.8	0.009b	II<III, IV
p62	0.36 ± 0.4	3.10 ± 3.3	8.69 ± 4.4	0.002b	II<III, IV

^*mean ± SD

^aKruskal-Wallis with Dunn's post hoc

^bOne-way ANOVA with Holm-Sidak post hoc