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. Author manuscript; available in PMC: 2018 Apr 1.
Published in final edited form as: Shock. 2017 Apr;47(4):402–408. doi: 10.1097/SHK.0000000000000764

Fig 1. Female patients present ChrX skewing during the clinical course of injury.

Fig 1

White blood cell DNA isolated from whole blood collected during the clinical course was tested for methylation at the polymorphic HUMARA locus as described in the material and methods section in order to determine ChrX inactivation ratios (XCI). For clarity of presentation, patients were stratified by degree of the observed XCI-ratio changes in response to trauma showing XCI-ratio changes less than 30% of initial (A); more or equal than 30% of initial (B); or extreme XCI (C). Panels D and E display the same patients showing XCI-ratio changes as percent of initial after starification by XCI changes less than 30% (D) or equal or more than 30% (E).