Table 2.
Baseline cardiac characteristics in participant with normal or low LV stroke index.
| Stroke index | ||||
|---|---|---|---|---|
| Variable | Normal (N=2,349) |
Low (N=536) |
p | Adjusted p |
| Left atrial dimension (cm) | 3.6 ± 0.4 | 3.3 ± 0.5 | 0.0001 | 0.0001 |
| Left atrial dimension index (cm/m) | 2.2 ± 0.3 | 2.0 ± 0.3 | 0.0001 | 0.0001 |
| LV end-diastolic diameter (cm) | 5.0 ± 0.4 | 4.6 ± 0.4 | 0.0001 | 0.0001 |
| LV end-diastolic diameter index (cm/m) | 3.1 ± 0.2 | 2.7 ± 0.1 | 0.0001 | 0.0001 |
| LV end-systolic diameter (cm) | 3.2 ± 0.4 | 3.0 ± 0.4 | 0.0001 | 0.0001 |
| Septal thickness (cm) | 0.9 ± 0.1 | 0.9 ± 0.1 | 0.78 | 0.05 |
| Posterior wall thickness (cm) | 0.9 ± 0.1 | 0.8 ± 0.1 | 0.06 | 0.50 |
| LV mass (g) | 157 ± 34 | 134 ± 31 | 0.0001 | 0.0001 |
| LV mass index (g/m2.7) | 42 ± 9 | 32 ± 7 | 0.0001 | 0.0001 |
| LV hypertrophy | 513 (22%) | 12 (2%) | 0.0001 | 0.0001 |
| Relative wall thickness | 0.36 ± 0.05 | 0.39 ± 0.06 | 0.0001 | 0.0001 |
| Concentric LV geometry | 117 (5%) | 93 (17%) | 0.0001 | 0.0001 |
| Stroke volume (ml) | 74 ± 11 | 59 ± 7 | ------ | ------ |
| Stroke index (ml/m2.04) | 27 ± 4 | 20 ± 2 | ------ | ------ |
| Cardiac output (l/min) | 4.9 ± 1.0 | 4.1 ± 0.8 | 0.0001 | 0.0001 |
| Cardiac index (l/min×m−1.83) | 2.0 ± 0.4 | 1.6 ± 0.3 | 0.0001 | 0.0001 |
| Ejection fraction(%) | 66 ± 5 | 63 ± 5 | 0.0001 | 0.0001 |
| Midwall fractional shortening (%) | 18 ± 2 | 16 ± 2 | 0.0001 | 0.0001 |
| Abnormal wall motion | 79 (3%) | 48 (9%) | 0.0001 | 0.02 |
Adjusted p: for the impact of age, sex, study center, BMI and systolic BP