Figure 2. Effects of rapamycin on response to oxygen stress.

A. ND2 mutant flies take longer to recover from anoxia-induced paralysis compared to WT controls. Rapamycin partially rescues this phenotype, but not to WT levels. Data are represented as mean +/- SEM. Significance was determined by ANOVA ***p < 0.001. B. Survival in 99.9% O₂. ND2 mutant flies are more susceptible to hyperoxia (solid red line) and rapamycin has no effect on response to hyperoxic stress (dashed red line).