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. 2016 Nov 15;7(49):80288–80297. doi: 10.18632/oncotarget.13375

Figure 2. 5-BDBD treatment attenuates OVA-induced airway inflammation in mice.

Figure 2

A. BALF differential cell count, B. Th2 cytokine concentration in supernatants of OVA re-stimulated MLN cells, C. histology of hematoxylin and eosin (H&E) stained lung sections of 5-BDBD and vehicle treated mice (Magnification: 20x objective) and D. BHR in response to increasing doses of inhaled methacholine, analyzed by recording the changes in airway resistance [R] and lung compliance [C], after the induction of an airway inflammation using OVA. Graphs show mean ±SEM (n = 5-6). * P < 0.05, ** P < 0.01 OVA/5-BDBD/OVA vs OVA/vehicle/OVA. # P < 0.05 OVA/vehicle/OVA vs PBS/vehicle/OVA