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. 2016 Nov 15;7(49):80288–80297. doi: 10.18632/oncotarget.13375

Figure 3. P2rx4 deficiency is accompanied by a reduction in salient features of experimental AAI.

Figure 3

A. Absolute number of neutrophils, eosinophils and lymphocytes in BALF, B. Th2 cytokine content in supernatants of allergen re-stimulated MLN cells and C. histology of H&E stained lung sections (Magnification: 20x objective) isolated from WT and P2rx4 mice after OVA-challenge. D. Methacholine mediated BHR represented as changes in airway resistance [R]. Graphs show mean ±SEM (n = 5-6). * P < 0.05, ** P < 0.01, *** P < 0.001, P2rx4 OVA/OVA vs P2rx4 OVA/OVA. # P < 0.05 OVA/OVA P2rx4 vs PBS/OVA P2rx4