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. 2016 Nov 15;7(49):80288–80297. doi: 10.18632/oncotarget.13375

Figure 6. P2rx4.deficient BMDCs exhibit an attenuated T-cell priming capacity in vitro and in vivo.

Figure 6

A. Th2 cytokine secretion of vehicle or OVA-primed WT and P2rx4-/- BMDCs cultured together with OVA-specific OTII CD4+ T cells. B. BALF differential cell count, C. Th2 cytokine levels in supernatants of OVA re-stimulated MLN cells and D. histology of H&E stained lung sections isolated from WT mice adoptively transferred with either vehicle- or OVA-primed P2rx4 or WT BMDCs after OVA-aerosol challenge. Graphs show mean ±SEM (n = 3-6). * P < 0.05, ** P < 0.01, *** P < 0.001 P2rx4 OVA BMDCs vs P2rx4+/+ OVA BMDCs.