Table 3. MST and censoring rate of Case 1A-1C.

	Case 1A (HR=4/9) : 71% power				Case 1B (HR=4/9) : 63% power				Case 1C (HR=4/9): 61% power
	MST		Censoring rate (Overall=45%)		MST		Censoring rate (Overall=43%)		MST		Censoring rate (Overall=55.5%)
	TREATMENT		TREATMENT		TREATMENT		TREATMENT		TREATMENT		TREATMENT
BIOMARKER	no	yes	no	yes	no	yes	no	yes	no	yes	no	yes
low (negative)	3 yrs	4 yrs	52%	61%	1 yr	2 yrs	17%	38%	3 yrs	4 yrs	52%	61%
high (positive)	1 yr	3 yrs	17%	52%	2 yrs	9 yrs	38%	80%	2 yr	6 yrs	38%	71%