Table 4. Multivariate analyses of variables in relation to five-year overall survival of patients with high CD8+ tumor-infiltrating lymphocytes.

Variables	Parameter	Hazard ratio (95% CI)	p-value
Lauren classification	Diffuse vs. intestinal	1. 102 (0. 647−1. 878)	0. 72
Tumor stage	pT2-4 vs. pT1	0. 282 (0. 081−0. 986)	0. 047*
Lymph node metastasis	Present vs. absent	0. 285 (0. 125−0. 651)	0. 003*
Lymphatic invasion	Present vs. absent	0. 633 (0. 367−1. 093)	0. 101
Perineural invasion	Present vs. absent	0. 602 (0. 355−1. 022)	0. 06
PD-L1	High vs. low	0. 045 (0. 089−0. 974)	0. 045*

^*Statistically significant p-values are indicated in boldface type.

Abbreviations: CI, confidence interval.