Table 1. Patients’ clinicopathologic features compared with KIF-2C expression.
| Variable | Cases, n (%) | KIF-2C, n (%) | P* | |
|---|---|---|---|---|
| <2.0 | ≥2.0 | |||
| Age (years) | 0.165 | |||
| ≤ 57.0† | 197(47.5) | 102(51.0) | 95(44.2) | |
| > 57.0 | 218(52.5) | 98 (49.0) | 120 (55.8) | |
| Sex | 0.148 | |||
| Male | 308(74.2) | 142 (71.0) | 166 (77.2) | |
| Female | 107 (25.8) | 58 (29.0) | 49 (22.8) | |
| Location | 0.443 | |||
| Upper | 26 (6.3) | 13 (6.5) | 13 (6.0) | |
| Middle | 286(68.9) | 132(66.0) | 154 (71.6) | |
| Lower | 103 (24.8) | 55 (27.5) | 48 (22.3) | |
| Differentiation | 0.022 | |||
| Well | 63 (15.2) | 40 (20.0) | 23 (10.7) | |
| Moderate | 277(66.7) | 129 (64.5) | 148 (68.8) | |
| Poor | 75 (18.1) | 31 (15.5) | 44 (20.5) | |
| pT status | 0.038 | |||
| T1 | 20 (4.8) | 13 (6.5) | 7 (3.3) | |
| T2 | 101 (24.3) | 39 (19.5) | 62 (28.8) | |
| T3 | 294(70.8) | 148 (74.0) | 146 (67.9) | |
| pN status | 0.713 | |||
| N0 | 227(54.7) | 112 (56.0) | 115 (53.5) | |
| N1 | 107(25.8) | 53 (26.5) | 54 (25.1) | |
| N2 | 65(15.7) | 27 (13.5) | 38 (17.7) | |
| N3 | 16(3.9) | 8 (4.0) | 8 (3.7) | |
| pTNM Stage | 0.962 | |||
| I | 24 (5.8) | 12 (6.0) | 12 (5.6) | |
| II | 233(56.1) | 111 (55.5) | 122 (56.7) | |
| III | 158(38.1) | 77 (38.5) | 81 (37.7) | |
| Surgery | 0.824 | |||
| Unqualified | 135 | 64 (32.0) | 71 (32.5) | |
| Qualified | 280 | 136 (68.0) | 144 (67.5) | |
| Total | 415(100) | 200(48.2) | 215(51.8) | |
pT, Pathologic tumor; pN, Pathologic node; Qualified surgery, R0 resection with at least 12 resected lymph nodes; Unqualified surgery, R0 resection with less than 12 resected lymph nodes.
*
Chi-square test
†
Median age