Table 3. Results of multivariable Cox regression analysis in the entire cohort.
| Prognostic Factor | Hazard ratio | 95% CI | P |
|---|---|---|---|
| OS | |||
| Sex (Male vs. Female) | 1.566 | 1.126-2.179 | 0.008 |
| Differentiation (Poor vs. Moderate vs. Well) | 1.055 | 0.838-1.328 | 0.647 |
| pT status (T3 vs. T2 vs. T1) | 1.345 | 1.023-1.769 | 0.034 |
| pN status (N3 vs. N2 vs. N1 vs.N0) | 2.014 | 1.733-2.341 | < 0.001 |
| Surgery (Qualified vs. Unqualified) | 0.539 | 0.404-0.720 | < 0.001 |
| KIF-2C (<2.0 vs. ≥2.0) | 1.259 | 0.959-1.654 | 0.097 |
| DFS | |||
| Sex (Male vs. Female) | 1.444 | 1.055-1.978 | 0.022 |
| Differentiation (Poor vs. Moderate vs. Well) | 1.108 | 0.885-1.387 | 0.369 |
| pT status (T3 vs. T2 vs. T1) | 1.307 | 1.006-1.698 | 0.045 |
| pN status (N3 vs. N2 vs. N1 vs.N0) | 1.984 | 1.711-2.300 | < 0.001 |
| Surgery (Qualified vs. Unqualified) | 0.608 | 0.460-0.803 | < 0.001 |
| KIF-2C (<2.0 vs. ≥2.0) | 1.213 | 0.931-1.579 | 0.152 |
CI: Confidence interval; pT, Pathologic tumor; pN, Pathologic node; OS, Overall survival; DFS, Disease-free survival; Qualified surgery, R0 resection with at least 12 resected lymph nodes; Unqualified surgery, R0 resection with less than 12 resected lymph nodes.