Table 2. Clinicopathological characteristics of HCC patients according to NRAS and YWHAZ expression.

Characteristics	NRAS mRNA expression (Mean ± SD)	p value	YWHAZ mRNA expression (Mean ± SD)	p value	NRAS protein expression (Mean ± SD)	p value	YWHAZ protein expression (Mean ± SD)	p value
Age (years)		0.9688		0.0343*		0.0051*		0.7443
≥ 60	10.41 ± 0.5563		12.97 ± 0.8093		0.03212 ± 0.1406		0.01065 ± 0.3677
< 60	10.40 ± 0.6507		13.15 ± 0.7579		−0.03000 ± 0.1510		0.02714 ±0.2695
Gender		0.6340		0.6491		0.2213		0.0683
Female	10.38 ± 0.5816		13.03 ± 0.8047		−0.02415 ± 0.1698		0.07746 ± 0.3911
Male	10.42 ± 0.6102		13.07 ± 0.7845		0.009835 ± 0.1460		−0.01600 ± 0.2923
Edmondson–Steiner grade		0.0130*		< 0.0001*		0.0002*		0.0111*
G1-2	10.34 ± 0.5769		12.91 ± 0.7726		0.03662 ± 0.1268		−0.02295 ± 0.3068
G3-4	10.51 ± 0.6300		13.32 ± 0.7524		−0.04835 ± 0.1692		0.1079 ± 0.3628
TNM stage		0.1187		0.4169		0.0702		0.2091
I–II	10.36 ± 0.5898		13.04 ± 0.7955		0.02140 ± 0.1468		−0.0005718 ± 0.3043
III–IV	10.47 ± 0.6057		13.12 ± 0.8017		-0.02070 ± 0.1446		0.06635 ± 0.3835
AFP level (ng/ml)		0.6538		0.0011*		< 0.0001*		0.0095*
≥ 400	10.40 ± 0.6461		13.29 ± 0.7759		−0.07200 ± 0.1501		0.1445 ± 0.4223
< 400	10.36 ± 0.5695		12.93 ± 0.7823		0.04388 ± 0.1234		-0.02912 ± 0.2743
Alcohol consumption		0.1878		0.6499		0.4258		0.9629
Yes	10.35 ± 0.5687		13.00 ± 0.8031		0.02566 ± 0.1423		0.01069 ± 0.3494
No	10.43 ± 0.5989		13.04 ± 0.7736		0.007446 ± 0.1476		0.008242 ± 0.3277
HBV/HCV infection		0.9849		0.5097		0.2440		0.4237
Yes	10.40 ± 0.5671		13.07 ± 0.7635		0.03754 ± 0.1193		−0.02553 ± 0.2648
No	10.40 ± 0.6132		13.01 ± 0.8081		0.006684 ± 0.1537		0.02321 ± 0.3561
Vascular invasion		0.6740		0.1856		0.0597		0.0151*
None	10.36 ± 0.6012		12.98 ± 0.7891		0.02779 ± 0.1344		−0.04272 ± 0.2652
Micro/macro	10.39 ± 0.5886		13.11 ± 0.7999		−0.01938 ± 0.1587		0.09696 ± 0.4233