Table 2. Correlation between the expression of Klotho and clinicopathological parameters in melanoma patients.
| Characteristics | Klotho expression | P value | ||||
|---|---|---|---|---|---|---|
| − | + | ++ | +++ | |||
| Age | ||||||
| <50 | 7 (17.1%) | 11 (26.8%) | 11 (26.8%) | 12 (29.3%) | 0.317 | |
| ≥50 | 5 (20.0%) | 11 (44.0%) | 6 (24.0%) | 3 (12.0%) | ||
| Gender | ||||||
| Male | 8 (26.7%) | 9 (30.0%) | 10 (33.3%) | 3 (10.0%) | 0.057 | |
| Female | 4 (11.1%) | 13 (36.1%) | 7 (19.4%) | 12 (33.3%) | ||
| Ulcer history | ||||||
| Yes | 4 (10.0%) | 15 (37.5%) | 11 (27.5%) | 10 (25.0%) | 0.202 | |
| No | 8 (30.8%) | 7 (26.9%) | 6 (23.1%) | 5 (19.2%) | ||
| Position | ||||||
| Limbs | 7 (15.6%) | 17 (37.8%) | 9 (20.0%) | 12 (26.7%) | 0.245 | |
| Truncus | 5 (23.8%) | 5 (23.8%) | 8 (38.1%) | 3 (14.3%) | ||
| Clinical stage | ||||||
| I-II | 5 (15.6%) | 11 (34.4%) | 4 (12.5%) | 12 (37.5%) | 0.015* | |
| III-IV | 7 (20.6%) | 11 (32.4%) | 13 (38.2%) | 3 (8.8%) | ||
| Clark level | ||||||
| I-IV | 5 (15.2%) | 8 (24.2%) | 12 (36.4%) | 8 (24.2%) | 0.178 | |
| V | 7 (21.2%) | 14 (42.4%) | 5 (15.2%) | 7 (21.2%) | ||
| Breslow thickness | ||||||
| <4mm | 4 (12.1%) | 11 (33.3%) | 8 (24.2%) | 10 (30.3%) | 0.383 | |
| ≥4mm | 8 (24.2%) | 11 (33.3%) | 9 (27.3%) | 5 (15.2%) | ||
*
P<0.05