Figure 1. Quantitative real-time PCR analysis of bacteria in CRC tumor and corresponding normal mucous samples, presented as log10 copies/g mucosa of 50 ng DNA.
The median abundance of Fusobacterium spp. (N = 97, p < 0.001, Wilcoxon signed rank test), E.faecalis (N = 97, p < 0.05, Wilcoxon signed rank test) and ETBF (N = 87, p < 0.001, Wilcoxon signed rank test) in CRC tissues was significantly higher than that in adjacent normal mucous tissues (10 cm beyond cancer margins), while there was no significance in E.coli (N = 96, p > 0.05, Wilcoxon signed rank test) between CRC tissue and adjacent normal mucous tissue.