Figure 6. Performance of small ncRNA-based signatures predicting recurrence-free survival in non-small cell lung cancer.
Risk groups as defined in the external dataset of (A) lung adenocarcinoma (LUAD, n = 107) and (B) lung squamous cell carcinoma (LUSC, n = 149). Kaplan-Meier curves of high risk groups (red) compared to the combined low and intermediate risk groups (turquoise) as defined by the miRNA+piRNA signature are shown. (C) LUAD patients and (D) LUSC patients are ordered by their miRNA signature-based risk classification (top) in order to illustrate the re-classification that occurs when the miRNA+piRNA signature (bottom) is applied to the dataset. Intermediate and low risk patients are represented by green and blue bars, respectively.