Figure 2. Assessment of combination therapy using colony formation assays revealed a synergistic cytotoxicity with GLV-1h68 and EBRT at 2 Gy.
A. Bar graph showing increased cytotoxicity with the addition of GLV-1h68 (MOI 0.01) to EBRT. B. photograph of clonogenic assay 6-well plates stained with crystal violet 10 days post-treatment. C. Bar Graph of the combination therapy with increasing viral MOI's and EBRT 2 and 4 Gy D. Bliss analysis of combination therapy (GLV-1h68 MOI 0.01, radiation at 2 and 4 Gy). (** = p value <0.01 and *** = p value <0.001).