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. 2016 Nov 7;7(49):81645–81660. doi: 10.18632/oncotarget.13162

Figure 9. Down-regulation of SPRY2 mRNA is associated with reduced overall and disease-free survival in patients with high-grade serous ovarian carcinoma.

Figure 9

The cBioPortal for Cancer Genomics was used to query high-grade serous ovarian carcinomas from The Cancer Genome Atlas (n=489) for patients with altered SPRY2 mRNA levels. A. OncoPrint results showing cases with altered SPRY2 mRNA levels across all 489 high-grade serous ovarian carcinomas. B. Overall (left panel) and disease-free (right panel) survival differences between samples without and with up-regulated SPRY2 mRNA were displayed as Kaplan-Meier survival curves with the associated P value (Log-rank test). C. Overall (left panel) and disease-free (right panel) survival differences between samples without and with down-regulated SPRY2 mRNA were displayed as Kaplan-Meier survival curves with the associated P value (Log-rank test).