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. 2016 Nov 7;7(49):81661–81669. doi: 10.18632/oncotarget.13163

Table 2. The distribution difference of mast cell sorted by clinical and molecular factors.

Variable N Average rank Z P
Age, year
 < 50 88 133.9 -4.589 <0.001
 ≥ 50 131 93.9
Max diameter of cancer (cm)
 ≤ 2.0 101 112.7 0.335 (χ2) 0.846
 2.0 - 5.0 111 107.7
 > 5.0 7 108.4
Histological type
 Invasive ductal carcinoma 210 107.9 -2.322 0.020
 Invasive lobular carcinoma 9 157.9
Lymph node metastasis
 Yes 128 108.7 -3.530 0.724
 No 91 111.8
ER
 Negative 72 91.4 -3.052 0.002
 Positive 147 119.1
PR
 Negative 76 95.3 -2.508 0.012
 Positive 143 117.8
HER-2
 Negative 167 111.9 -0.807 0.420
 Positive 52 103.8
Ki67
 ≤ 14% 49 132.8 -2.861 0.004
 > 14% 170 103.4
Molecular typing
 Luminal A 39 133.8 13.423(χ2) 0.004
 Luminal B 95 112.8
 HER-2 overexpression 53 105.9
 ER-, PR- and HER-2- 32 79.4

Abbreviations: ER+, estrogen receptor positive; PR+, progesterone receptor positive; HER-2+, human epidermal growth factor receptor-2 positive; Ki67, Ki67 nuclear antigen; N, number of subjects in each group; Z, Z-value.