Table 3. Multivariate analysis of overall survival of patients.

Characteristic	HR(95%CI)	P value
Sex (male vs. female)	0.800(0.566-1.133)	0.209
Age (< 65 vs. ≥ 65 years)	1.262(0.908-1.755)	0.166
Smoking status	0.995(0.735-1.347)	0.995
T stage (T1-2 vs T3-4)	1.705(1.200-2.424)	0.003
N stage (N0 vs N1-3)	0.773(0.421-1.419)	0.406
miRNA signature	2.809(1.812-4.355)	<0.001