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. 2016 Aug 30;7(49):81888–81898. doi: 10.18632/oncotarget.11702

Table 3. Factors associated with ipsilateral breast tumor relapse (IBTR) among patients who received accelerated whole breast irradiation (AWBI) and conventional whole breast irradiation (CWBI).

AWBI+CWBI (N=660) AWBI (N=330) CWBI (N=330)
5-year event rate (%) Log-rank P 5-year event rate (%) Log-rank P 5-year event rate (%) Log-rank P
Total 1.2 - 0.8 - 1.8 -
Age (y) 0.83 0.83 0.69
<50 1.2 0.6 1.8
≥50 1.2 0.7 1.8
Histology 0.26 0.51 0.34
Ductal 1.4 0.7 2.0
Others 0 0 0
Pathologic T stage 0.65 0.37 0.98
T1 1.1 0.5 0.8
T2 1.5 1.0 4.1
Pathologic N stage 0.26 0.06 0.99
N0 1.1 0.4 1.8
N1 2.0 2.1 2.1
Resection margin 0.53 0.74 0.58
>1mm 1.3 0.7 1.9
≤1mm 0 0 0
Tumor grade 0.01 0.08 0.10
Low-Intermediate 0.3 0 0.5
High 2.9 1.9 3.8
Molecular subtype 0.35 0.76 0.37
Luminal 0.8 0.4 1.3
Non-luminal 2.5 1.6 3.2
Ki-67 index 0.07 0.08 0.06
<14% 0.9 0 1.4
≥14% 2.2 1.4 6.0
Chemotherapy 0.67 0.87 0.46
Yes 1.2 0.4 3.1
No 1.4 1.4 0
Hormone therapy 0.28 0.13 0.95
Yes 1.2 0.4 1.3
No 1.3 1.5 3.3