Table 1.
Men | Postmenopausal women | |||||||||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Osteoporotic fractures | no | yes | p | no | yes | p | ||||||||||
The number of subjects | 181 | 7 | 144 | 24 | ||||||||||||
Age (years) | 62.8 | ± | 9.6 | 63.9 | ± | 3.8 | 0.780 | 65.7 | ± | 9.0 | 69.3 | ± | 7.3 | 0.073 | ||
Duration of diabetes (years) | 9.6 | ± | 9.2 | 16.9 | ± | 16.3 | 0.049 | 10.9 | ± | 9.3 | 13.1 | ± | 8.9 | 0.288 | ||
BMI (kg/m²) | 23.7 | ± | 4.2 | 22.1 | ± | 3.1 | 0.312 | 24.7 | ± | 4.5 | 25.1 | ± | 2.5 | 0.636 | ||
HbA1c (%) | 8.7 | ± | 2.0 | 8.0 | ± | 2.2 | 0.363 | 8.6 | ± | 2.2 | 8.2 | ± | 2.2 | 0.403 | ||
Serum albumin (g/dL) | 4.3 | ± | 0.4 | 4.1 | ± | 0.4 | 0.250 | 4.1 | ± | 0.5 | 4.2 | ± | 0.5 | 0.334 | ||
Serum calcium (mg/dL) | 9.3 | ± | 0.4 | 9.0 | ± | 0.3 | 0.115 | 9.2 | ± | 0.3 | 9.2 | ± | 0.3 | 0.918 | ||
Serum phosphate (mg/dL) | 3.3 | ± | 0.5 | 3.5 | ± | 0.7 | 0.531 | 3.7 | ± | 0.5 | 3.7 | ± | 0.5 | 0.904 | ||
Serum creatinine (mg/dL) | 0.80 | ± | 0.21 | 0.83 | ± | 0.18 | 0.719 | 0.63 | ± | 0.25 | 0.76 | ± | 0.36 | 0.026 | ||
Serum IGF-I (ng/mL) | 153 | ± | 51 | 128 | ± | 37 | 0.191 | 138 | ± | 52 | 125 | ± | 38 | 0.068 | ||
L-BMD (g/cm²) | 1.042 | ± | 0.176 | 1.032 | ± | 0.396 | 0.896 | 0.887 | ± | 0.187 | 0.874 | ± | 0.203 | 0.758 | ||
L-Z score | 0.47 | ± | 1.06 | 0.30 | ± | 2.21 | 0.706 | 0.62 | ± | 1.23 | 0.75 | ± | 1.37 | 0.646 | ||
Insulin treatment | 30 | 3 | 0.094 | 42 | 9 | 0.390 | ||||||||||
Oral hypoglycemic agents | 81 | 3 | 0.911 | 54 | 7 | 0.439 |
BMI: body mass index, HbA1c: hemoglobin A1c, IGF-I: insulin-like growth factor-I, L: lumbar, BMD: bone mineral density