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Dkk-3 upregulates the intracellular VEGF expression level. RTPCR (A,B), immunocytochemical (C,D), western blot analysis (E,F) of VEGF in HUVECs incubated with hrDkk-3 (1 ng/ml or 10 ng/ml) for either 6 or 12 h. Values are means ± SEM. *p < 0.05 vs. baseline condition; **p < 0.001 vs. baseline condition.
