Table 3.

Genes displaying altered expression in MeCP2-deficient systems that encode oxidative defense factors.

Gene	Coding genome	Protein function	Δ	Cell/ tissue type	Organism	References
SOD1	nDNA	ROS scavenging enzyme	↑	Hippocampus	MeCP2-null mice	Großer et al., 2012
				Lympho-monocytes	Human (RTT patients)	Pecorelli et al., 2013
CAT	nDNA	Catalase	↑	Lympho-monocytes	Human (RTT patients)	Pecorelli et al., 2013
PRDX1	nDNA	Peroxiredoxin	↑
GSTO1	nDNA	Glutathione S-transferase omega 1	↑
MGST2, MGST3	nDNA	Microsomal glutathione S-transferase	↑
Prdh	nDNA	Proline dehydrogenase	↑	Brain tissue	MeCP2-null mice	Urdinguio et al., 2008
Ucp3	nDNA	Uncoupling protein 3	↓	Skeletal muscles	MeCP2-null mice	Gold et al., 2014