Table 2.
Mitochondrial DNA in cultured murine fibroblasts.
Cells | wtF | Cav1−/− fibroblasts | Cav2−/− fibroblasts | |||
---|---|---|---|---|---|---|
−FasL | +FasL | −FasL | +FasL | −FasL | +FasL | |
Total DNA mass* (pg/cell) | 8.1 ± 1.8 (n = 6) | 9.4 ± 0.87 (n = 5) | 9.4 ± 1.1 (n = 5) | 10.4 ± 0.8 (n = 7) | 9.83 ± 1.1 (n = 6) | 10.5 ± 0.9 (n = 7) |
mtDNA- copies (per cell) | 844 ± 192 (n = 6) | 882 ± 234 (n = 5) | 863 ± 191 (n = 5) | 915 ± 188 (n = 7) | 857 ± 205 (n = 6) | 908 ± 155 (n = 7) |
The predicted mass of a diploid mouse genome of 2.8 × 109 base pairs is 3.3 pg/cell.