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. 2016 Dec 22;13(2):595–603. doi: 10.3892/etm.2016.3992

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Copyright: © Zhang et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — ABZ alters the expression levels of cell cycle regulatory proteins. (A) Cells were treated with ABZ for 18 h and analyzed using immunofluorescence staining for cyclin B1. (a) control cells showing low levels of cyclin B1 and (b and c) treated cells showing markedly elevated cyclin B1. DAPI was used for nuclear staining. Representative images were captured under a fluorescence microscope (magnification, ×1,000). (B) Western blot analysis of cell cycle regulatory proteins. (C) Histogram demonstrating Cdc2, cyclin A2 and cyclin B1 protein expression levels. *P<0.05 vs. control group. ABZ, albendazole; Cdc2, cell division control protein 2 homolog.