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. 2016 Dec 29;13(2):429–436. doi: 10.3892/etm.2016.4013

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Copyright: © Si et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 4. — Functional and electrophysiological outcomes of the regenerated nerve fibres. (A) SFI values were nearly all −100 immediately following bridging surgery (group A, −88 to −99; group B, −89 to −98; and group C, −87 to −98), and with no significant differences among the three groups. At 6 and 12 weeks post-surgery, varying degrees of neural recovery were observed in each group, and the recovery of SFI in the bFGF-PLGA microspheres and bFGF groups were quicker when compared with the PBS group. The greatest recovery was observed in the bFGF-PLGA microspheres group. (B) At 12 weeks post-surgery, the NCV, ACMAP and AREA in bFGF-PLGA microspheres and bFGF groups showed significant restoration compared with the PBS group, and there was also a significant difference between the bFGF group and the PBS group *P<0.05. SFI, sciatic function index; bFGF, basic fibroblast growth factor; PLGA, poly-lactic-co-glycolic acid; NCV, nerve conduction velocity; ACMAP, amplitude of compound muscle action potential; AREA, fractional area.