Fig. 3.

Effect of phytocomplexes on lymphatic endothelial cell permeability induced by IL-1β. HDLEC were treated with plant extracts: flavonoids from buckwheat (a); non-flavonoid phenols from dandelion (b); saponins from butcher's broom(c); flavonoids from goldenrod and java tea (d), or their association (AdipoDren®) (e) for 18 h; rutin (5 µg/mL) was used as a positive control (f). g HDBEC were treated with AdipoDren® (10 μg/mL, 18 h). FITC-dextran transcellular transport was measured after 1 h of stimulation with IL-1β (10 ng/mL). n = 3. * p < 0.05, ** p < 0.01, and *** p < 0.001 versus basal; ^#p < 0.05 and ^###p < 0.001 versus IL-1β alone.