Table 4.

Serious events in the control and intervention period

Parameter	Control period (n = 2139)	Intervention period (n = 2263)	p
Number of patients with serious events	208 (9.72)	166 (7.34)	0.005
Total number of serious events	268 (12.53)	185 (8.17)	<0.001
Acute myocardial infarction	4 (0.19)	0	0.056
Pulmonary embolism	3 (0.14)	2 (0.09)	0.679
Acute pulmonary edema	5 (0.23)	1 (0.04)	0.115
Respiratory failure	19 (0.89)	10 (0.44)	0.070
Stroke	0	0	1.000
Severe sepsis	21 (0.98)	1 (0.04)	<0.001
Acute renal failure	3 (0.14)	1 (0.04)	0.361
Emergency admission to the ICU	26 (1.22)	21 (0.93)	0.355
Cardiopulmonary arrest	14 (0.66)	2 (0.09)	0.002
Death	173 (8.09)	147 (6.50)	0.042

Serious events occurred after admission to the study ward and were not the reason for admission. Data expressed as number (%). Denominator: all patients admitted to the study wards (2139 patients in control period, 2263 patients in intervention period). Fisher’s exact test was used instead of the normal approximation test if the number of events in either sample was fewer than five