Table 2.

Colonoscopy findings, clinical and laboratory data at time of diagnosis of IBD of the patients

Patient	1	2	3
Time between diagnoses of sJIA and IBD	0.9 years	4.4 years	4.7 years
Time between start of Anti-IL1 agent and IBD	0.9 years	2.2 years	4.4 years
Anti-IL1 agents, dosage	Anakinra, 1.3 mg/kg	Canakinumab, 1.8 mg/kg	Anakinra, 0.7 mg/kg
Other medications	None	Cyclosporin A	None
Colonoscopy, macroscopic findings	Active, ulcerous ileitis and colitis, consistent with Crohn’s disease	Active colitis from sigmoid to coecum, consistent with Crohn’s disease	Colitis in colon descendens, consistent with ulcerative colitis
Colonoscopy, microscopic findings	Granulomatous inflammation	Inflammatory infiltrate	Inflammatory infiltrate
Diarrhea	Present	Present	Present
Macroscopic blood in stool	Absent	Absent	Present
Ferritin	138 ng/ml (9–80)	154 ng/ml (30–400)	10 ng/ml (30–400)
CRP	12.1 mg/dl (< 0.8)	4.67 mg/dl (0.02–1.0)	0.44 mg/dl (0.2–1.0)
Calprotectin/stool	Not available	877 μg/g (<50)	1264 μg/g (<50)

normal values in parentheses